Ift25tm1b(EUCOMM)Wtsi
Targeted Allele Detail
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| Symbol: |
Ift25tm1b(EUCOMM)Wtsi |
| Name: |
intraflagellar transport 25; targeted mutation 1b, Wellcome Trust Sanger Institute |
| MGI ID: |
MGI:5426875 |
| Synonyms: |
Ift25null1 |
| Gene: |
Ift25 Location: Chr4:107110889-107137135 bp, + strand Genetic Position: Chr4, 50.18 cM
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| Alliance: |
Ift25tm1b(EUCOMM)Wtsi page
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| IMPC: |
Ift25 gene page |
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| Mutant Cell Line: |
EPD0039_5_G06 |
| Germline Transmission: |
Earliest citation of germline transmission:
J:184749
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| Parent Cell Line: |
JM8.N4 (ES Cell)
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| Strain of Origin: |
C57BL/6N
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| Project Collection: |
EUCOMM
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| Allele Type: |
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Targeted (Null/knockout, Reporter) |
| Mutations: |
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Insertion, Intragenic deletion
Vector: L1L2_gt2
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Mutation details: The L1L2_gt2 cassette was inserted at position 106945715 of Chromosome 4 upstream of the critical exon(s) (Build 37). The cassette is composed of an FRT flanked lacZ/neomycin sequence followed by a loxP site. An additional loxP site is inserted downstream of the targeted exon(s) at position 106946668. The critical exon(s) is/are thus flanked by loxP sites. Cre mediated recombination deleted exon 3. Western blot analysis confirmed the absence of protein expression in homozygous mice.
(J:184749)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Ift25 Mutation: |
10 strains or lines available
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| Original: |
J:184749 Keady BT, et al., IFT25 Links the Signal-Dependent Movement of Hedgehog Components to Intraflagellar Transport. Dev Cell. 2012 May 15;22(5):940-51 |
| All: |
3 reference(s) |
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Analysis Tools
