Tg(Nfat1c-cre)1Bz Transgene Detail MGI Mouse (MGI:5430637)

Tg(Nfat1c-cre)1Bz
Transgene Detail

Summary

Symbol:	Tg(Nfat1c-cre)1Bz
Name:	transgene insertion 1, Bin Zhou
MGI ID:	MGI:5430637
Synonyms:	Nfatc1^enCre
Transgene:	Tg(Nfat1c-cre)1Bz Location: unknown
Alliance:	Tg(Nfat1c-cre)1Bz page

Transgene
origin

Strain of Origin:

Not Specified

Transgene
description

Transgene Type:

Transgenic (Recombinase)

Mutation:

Insertion

Tg(Nfat1c-cre)1Bz expression driven by 1 gene

Mutation details: A construct was generated in which a nuclear localized cre recombinase sequence (nlscre) was inserted between an HSPA1B (HSP68) minimal promoter and a 4.1 kb Nfatc1 intron 1 fragment (Nfatc1 enhancer). This construct was microinjected into fertilized eggs. Multiple lines were obtained. Specific founder information was not available. (J:185683)

Recombinase
activity

Activity:	Tissue activity of this recombinase allele
Driver:	Nfatc1 (species not specified) Summary of all recombinase alleles driven by Nfatc1.

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Expression

In Mice Carrying this Mutation:

2 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

Original:	J:185683 Wu B, et al., Nfatc1 coordinates valve endocardial cell lineage development required for heart valve formation. Circ Res. 2011 Jul 8;109(2):183-92
All:	9 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/19/2024 MGI 6.24