Tg(Msx3-icre)1/1Wdr
Transgene Detail
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| Symbol: |
Tg(Msx3-icre)1/1Wdr |
| Name: |
transgene insertion 1/1, William D Richardson |
| MGI ID: |
MGI:5430776 |
| Synonyms: |
line 1/1, Msx3-cre, Msx3/iCre |
| Transgene: |
Tg(Msx3-icre)1/1Wdr Location: unknown
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| Alliance: |
Tg(Msx3-icre)1/1Wdr page
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| Strain of Origin: |
Not Specified
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| Transgene Type: |
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Transgenic (Recombinase) |
| Mutation: |
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Insertion
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Tg(Msx3-icre)1/1Wdr expression driven by
1 gene
Transgene expression driven by:
| Organism |
Driver Gene |
Note |
| Not Specified |
Msx3 |
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Mutation details: A targeting vector was used to insert a codon improved cre recombinase (icre) and an Frt-flanked chloramphenicol selection cassette into exon 1 of the Msx3 locus in a phage artificial chromosome (PAC 402-G09) by homologous recombination. This resulted in fusing the icre sequence to the ATG of Msx3. The selection cassette was removed by induction of Flpe in EL250 cells, and the purified vector was used for pronuclear injection. 8 founders were obtained. Of these 2 were studied in more detail (1/1 and 3/2), displaying identical patterns of cre expression and GFP expression when crossed to ROSA-GFP reporter mice. Line 1/1 was used for derivation of animals for experimental study.
(J:186011)
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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Msx3
(species not specified)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:186011 Fogarty MH, Fate-mapping the mouse neural tube by Cre-loxP transgenesis. PhD Thesis - University of London. 2006; |
| All: |
4 reference(s) |
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Analysis Tools
