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Lpar5tm1Jch
Targeted Allele Detail
Summary
Symbol: Lpar5tm1Jch
Name: lysophosphatidic acid receptor 5; targeted mutation 1, Jerold Chun
MGI ID: MGI:5431493
Gene: Lpar5  Location: Chr6:125044883-125059435 bp, + strand  Genetic Position: Chr6, 59.21 cM
Alliance: Lpar5tm1Jch page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:185624
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation details: Most of the coding sequence was replaced with EGFP and a floxed neo cassette. The absence of transcript expression in the thymus, spleen and bone marrow. (J:185624)
Generation of the Lpar5tm1Jch allele
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Lpar5 Mutation:  29 strains or lines available
References
Original:  J:185624 Lin ME, et al., Targeted deletion of LPA5 identifies novel roles for lysophosphatidic acid signaling in development of neuropathic pain. J Biol Chem. 2012 May 18;287(21):17608-17
All:  3 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory