Tg(YAC128)55Hay
Transgene Detail
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| Symbol: |
Tg(YAC128)55Hay |
| Name: |
transgene insertion 55, Michael Hayden |
| MGI ID: |
MGI:5432147 |
| Synonyms: |
HD55, YAC128 |
| Transgene: |
Tg(YAC128)55Hay Location: unknown
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| Alliance: |
Tg(YAC128)55Hay page
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| Transgene Type: |
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Transgenic (Humanized sequence, Inserted expressed sequence) |
| Mutation: |
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Insertion
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Tg(YAC128)55Hay expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Homolog in Mouse |
Note |
| human |
HTT (3064) |
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Mutation details: A YAC containing a full-length human huntingtin gene under the control of the endogenous human HDH promoter was modified with a 128 CAG repeat expansion. The resulting construct (YAC128) was used to generate transgenic mice. Founder line 55 integrated the fewer copies of the transgene and had lower levels of protein expression compared to line 53.
(J:84453)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:84453 Slow EJ, et al., Selective striatal neuronal loss in a YAC128 mouse model of Huntington disease. Hum Mol Genet. 2003 Jul 1;12(13):1555-67 |
| All: |
19 reference(s) |
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Analysis Tools
