Tg(Crx-Atoh7,-cre)251Gla
Transgene Detail
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| Symbol: |
Tg(Crx-Atoh7,-cre)251Gla |
| Name: |
transgene insertion 251, Tom Glaser |
| MGI ID: |
MGI:5433215 |
| Synonyms: |
Crx>Math5 Tg (line 251) |
| Transgene: |
Tg(Crx-Atoh7,-cre)251Gla Location: unknown
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| Alliance: |
Tg(Crx-Atoh7,-cre)251Gla page
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| Strain of Origin: |
(C57BL/6J x SJL/J)F2 or (B6;129-Gt(ROSA)26Sortm1Sho/J x (C57BL/6 x SJL)F1)
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| Transgene Type: |
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Transgenic (Recombinase) |
| Mutation: |
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Insertion
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Tg(Crx-Atoh7,-cre)251Gla expression driven by
1 gene
Transgene expression driven by:
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Mutation details: The Atoh7 (Math5) and cre recombinase cDNAs, separated by an internal ribosomal entry site (IRES) and followed by an SV40 polyadenylation sequence, were cloned into a plasmid upstream of a 2.4 kb fragment of the mouse Crx gene that contained the promoter and proximal regulatory region. The linearized purified transgene was injected into fertilized oocytes. 2 founders and 2 lines were obtained, crossed to GFP reporter mice and analyzed for GFP and cre expression. A representative line, 251, was chosen for further analysis.
(J:186563)
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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Crx
(mouse)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:186563 Prasov L, et al., Pushing the envelope of retinal ganglion cell genesis: Context dependent function of Math5 (Atoh7). Dev Biol. 2012 Aug 15;368(2):214-30 |
| All: |
2 reference(s) |
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Analysis Tools
