Tg(Col11a2-cre)4Nhzi
Transgene Detail
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| Symbol: |
Tg(Col11a2-cre)4Nhzi |
| Name: |
transgene insertion 4, Nobumichi Hozumi |
| MGI ID: |
MGI:5435262 |
| Synonyms: |
alpha2(XI) collagen-Cre line #4 |
| Transgene: |
Tg(Col11a2-cre)4Nhzi Location: unknown
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| Alliance: |
Tg(Col11a2-cre)4Nhzi page
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| Transgene Type: |
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Transgenic (Recombinase) |
| Mutation: |
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Insertion
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Tg(Col11a2-cre)4Nhzi expression driven by
1 gene
Transgene expression driven by:
| Organism |
Driver Gene |
Note |
| Not Specified |
Col11a2 |
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Mutation details: Cre recombinase replaced the beta-galactosidase gene in a construct containing the -742bp Col11a2 promoter sequence, SV40 RNA splice site, lacZ sequence, and Col11a2 first intron. The 4.2 kb construct was microinjected into fertilized pronuclei. 5 founders were obtained. 2 lines (1 and 5) did show recombination in crosses to lacZ reporter mice. Line 2 showed cre activity in neural tissue and line 3 had ubiquitous activity. Line 4 was chosen due to its restricted cre activity pattern, although it had a low transgene copy number compared to the other lines.
(J:187063)
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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Col11a2
(species not specified)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:187063 Fujimaki R, et al., Expression of Cre recombinase in the mouse developing chondrocytes driven by the mouse alpha2(XI) collagen promoter. J Bone Miner Metab. 2005;23(3):270-3 |
| All: |
1 reference(s) |
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Analysis Tools
