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Tg(Wnt11-TagRFP/cre/ERT2)28Amc
Transgene Detail
Summary
Symbol: Tg(Wnt11-TagRFP/cre/ERT2)28Amc
Name: transgene insertion 28, Andrew P McMahon
MGI ID: MGI:5435691
Synonyms: Wnt11-myrTagRFP-IRES-CE
Transgene: Tg(Wnt11-TagRFP/cre/ERT2)28Amc  Location: unknown  
Alliance: Tg(Wnt11-TagRFP/cre/ERT2)28Amc page
Transgene
origin
Strain of Origin:  (C57BL/6 x DBA)F1
Transgene
description
Transgene Type:    Transgenic (Inducible, Recombinase, Reporter)
Inducer:    tamoxifen
Mutation:    Insertion
 
Tg(Wnt11-TagRFP/cre/ERT2)28Amc expression driven by 1 gene
 
Mutation details: A targeting construct containing a myristoylated Tag-RFPT variant of Red Fluorescent Protein, cre/ERT2, and FRT site flanked Kanamycin/neomycin selection cassette was inserted into the consensus start ATG codon of the mouse Wnt11 gene in the RP23-122D14 BAC. The PGK-Neo/Kan cassette was removed by transient Flpe-recombinase expression. The resulting modified Wnt11-myrTagRFP-IRES-CE BAC transgene was microinjected into (C57BL/6 x DBA) F1 donor eggs. Founder line 28 was subsequently established. (J:159099, J:187213)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Wnt11 (mouse)
Summary of all recombinase alleles driven by Wnt11.
 

Expression
In Mice Carrying this Mutation: 1 RNA-Seq or microarray experiment(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:187213 McMahon AP, Generation of a Wnt11-TagRFP/cre/ERT2 transgene. MGI Direct Data Submission. 2012;
All:  8 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory