Etl4<tm1(cre)Kymm> Targeted Allele Detail MGI Mouse (MGI:5435947)

Etl4^tm1(cre)Kymm
Targeted Allele Detail

Summary

Symbol:	Etl4^tm1(cre)Kymm
Name:	enhancer trap locus 4; targeted mutation 1, Ken-ichi Yamamura
MGI ID:	MGI:5435947
Synonyms:	Skt^cre
Gene:	Etl4 Location: Chr2:19915018-20815346 bp, + strand Genetic Position: Chr2, 14.27 cM, cytoband A3
Alliance:	Etl4^tm1(cre)Kymm page

Mutation
origin

Strain of Origin:

(C57BL/6NCrlj x CBA/JNCrlj)F1

Mutation
description

Allele Type:

Targeted (RMCE-ready, Recombinase)

Mutation:

Insertion

Etl4^tm1(cre)Kymm expression driven by 1 gene

Mutation details: Cre recombinase was inserted into intron 14 of the Etl4 (Skt) locus by recombinase mediated cassette exchange using an exchangeable gene trap system using left element/right element (LE/RE) mutant lox sites. The IRES-cre sequence was exchanged with the IRES-lacZ-neo unit in the original trap vector by co-electroporation of the vector and pCAGGS-cre into TT2 ES cells containing the trapped Etl4 gene. (J:187217)

Generation of the Etl4^tm1(cre)Kymm allele.

Recombinase
activity

Activity:	Tissue activity of this recombinase allele
Driver:	Etl4 (mouse) Summary of all recombinase alleles driven by Etl4. Alliance mouse Etl4 gene page

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available
Carrying any Etl4 Mutation:	485 strains or lines available

References

Original:	J:187217 Abe K, et al., A Cre knock-in mouse line on the Sickle tail locus induces recombination in the notochord and intervertebral disks. Genesis. 2012 Oct;50(10):758-65
All:	1 reference(s)

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