About   Help   FAQ
Adartm2Knk
Targeted Allele Detail
Summary
Symbol: Adartm2Knk
Name: adenosine deaminase, RNA-specific; targeted mutation 2, Kazuko Nishikura
MGI ID: MGI:5436438
Gene: Adar  Location: Chr3:89622329-89660753 bp, + strand  Genetic Position: Chr3, 39.19 cM, cytoband F2
Alliance: Adartm2Knk page
Mutation
origin
Mouse Generated:  Earliest citation of chimera generation: J:65981
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    Exons 12 and 13 which encode part of the catalytic domain were replaced by a PGK-neomycin cassette. (J:65981)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Adar Mutation:  72 strains or lines available
References
Original:  J:65981 Wang Q, et al., Requirement of the RNA editing deaminase ADAR1 gene for embryonic erythropoiesis. Science. 2000 Dec 1;290(5497):1765-8
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory