b2b1117.1Clo
Chemically induced Allele Detail
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| Symbol: |
b2b1117.1Clo |
| Name: |
Mutant line 1117.1; Bench to Bassinet Program (B2B/CVDC), mutation 1117, subline 1 Cecilia Lo |
| MGI ID: |
MGI:5437731 |
| Gene: |
b2b1117.1Clo Location: unknown
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| Alliance: |
b2b1117.1Clo page
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Mutant 1117-007-NA shows a single great artery arising from ventricles with right sided aortic arch
Show the 9 phenotype image(s) involving this allele.
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| Strain of Origin: |
C57BL/6J
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| Project Collection: |
B2B/CvDC
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| Allele Type: |
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Chemically induced (ENU) |
| Mutation: |
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Single point mutation
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Mutation details: This ENU-induced mutation was isolated in a screen at the University of Pittsburgh. It is a subline of b2b1117Clo. The molecular lesion is in the Kif15 gene.
(J:175213)
Additional
incidental mutations
were detected in sequencing for the causative mutation,
b2b1117.1Clo, and may be present in stocks carrying this mutation.
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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| Carrying any b2b1117.1Clo Mutation: |
1 strain or line available
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This mutation was derived from the parent line b2b1117Clo.
Summative Diagnosis:
Mutant Type 1:
Cardiac phenotype: Pulmonary atresia, ventricular septal defect (VSD) and major aortopulmonary collateral arteries (MAPCA)
Noncardiac phenotype: Facial cleft, micrognathia
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Analysis Tools
