Summary | Mutation origin | Mutation description | Expression | Phenotypes | Disease models | Tumor data | Find Mice (IMSR) | References

Symbol:	Usp9xtm1Tuv
Name:	ubiquitin specific peptidase 9, X chromosome; targeted mutation 1, David A Tuveson
MGI ID:	MGI:5438072
Synonyms:	Usp9xfl, Usp9xloxP
Gene:	Usp9x  Location: ChrX:12937737-13039567 bp, + strand  Genetic Position: ChrX, 7.95 cM
Alliance:	Usp9xtm1Tuv page

Germline Transmission:	Earliest citation of germline transmission: J:186717
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: A loxP site was inserted upstream of exon 3. An FRT-flanked neo cassette with a 3' loxP site was inserted downstream of exon 3. (J:186717)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	15 assay results 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	4 anatomical structure(s)

List all tumor models in MMHCdb carrying Usp9xtm1Tuv

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Usp9x Mutation:	24 strains or lines available

Original:	J:186717 Perez-Mancera PA, et al., The deubiquitinase USP9X suppresses pancreatic ductal adenocarcinoma. Nature. 2012 Jun 14;486(7402):266-70
All:	11 reference(s)