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Gene Expression Data
Assay Details
Assay
Reference: J:30900 Banfi S, et al., Cloning and developmental expression analysis of the murine homolog of the spinocerebellar ataxia type 1 gene (Sca1). Hum Mol Genet. 1996 Jan;5(1):33-40
Assay type: RNA in situ
MGI Accession ID: MGI:5438522
Gene symbol: Atxn1
Gene name: ataxin 1
Probe: M1
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 3A: postnatal adult (more )
Structure Level Pattern Image Note
TS28: brain Present Widespread 3A Expression is present in neurons throughout the brain.
TS28: cerebellar cortex Present 3A
TS28: corpus striatum Present 3A
TS28: hippocampal formation Present 3A
TS28: neocortex Present 3A
TS28: superior colliculus Present 3A
TS28: thalamus Present 3A
Specimen 3C: postnatal adult (more )
Structure Level Pattern Image Note
TS28: brainstem Weak 3C Expression levels were not enhanced in brain regions that show neurodegeneration during spinocerebellar ataxia type 1.
TS28: inferior olivary nucleus Weak 3C Expression levels were not enhanced in brain regions that show neurodegeneration during spinocerebellar ataxia type 1.
TS28: pons Weak 3C Expression levels were not enhanced in brain regions that show neurodegeneration during spinocerebellar ataxia type 1.
Specimen 3D: postnatal adult (more )
Structure Level Pattern Image Note
TS28: cerebral cortex Present 3D Expression is present in distinct, large cells, consistent with neuronal expression.
Specimen 3E: postnatal adult (more )
Structure Level Pattern Image Note
TS28: dentate gyrus Strong 3E
TS28: hippocampus pyramidal cell layer Strong 3E
Specimen 3F: postnatal adult (more )
Structure Level Pattern Image Note
TS28: cerebellum internal granule cell layer Strong 3F
Specimen Not shown: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: cerebellum Present
Specimen 4: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: cerebellum Present Regionally restricted 4B Expression is present in the external granule cell layer and the Purkinje cell layer. No expression was detected in deep cerebellar nuclei.
Specimen 5B: postnatal day 9 (more )
Structure Level Pattern Image Note
TS28: cerebellar cortex Present 5B
Specimen 5D: postnatal day 14 (more )
Structure Level Pattern Image Note
TS28: cerebellar cortex Present 5D
TS28: cerebellum Purkinje cell layer Strong 5D
Specimen 5G: postnatal day 21 (more )
Structure Level Pattern Image Note
TS28: cerebellar cortex Present 5G
Specimen 5I: postnatal adult (more )
Structure Level Pattern Image Note
TS28: cerebellar cortex Present 5I
Specimen 6A: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: cerebral cortex ventricular layer Present 6A
TS22: gut Present 6A
TS22: liver Present 6A
TS22: metanephros Present 6A
TS22: axial skeleton Strong 6A There is prominent expression along the vertebral column.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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09/17/2024
MGI 6.24 		The Jackson Laboratory