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Usp46Gt(pU17)1Imeg
Gene trapped Allele Detail
Summary
Symbol: Usp46Gt(pU17)1Imeg
Name: ubiquitin specific peptidase 46; gene trap 1, Institute of Molecular Embryology and Genetics
MGI ID: MGI:5438668
Gene: Usp46  Location: Chr5:74159387-74229070 bp, - strand  Genetic Position: Chr5, 39.33 cM
Alliance: Usp46Gt(pU17)1Imeg page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:187828
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  (C57BL/6 x CBA)F1
Mutation
description
Allele Type:    Gene trapped (Null/knockout, Reporter)
Mutation:    Insertion of gene trap vector
 
Mutation details: The pU17 gene trap vector (floxed beta-geo cassette, polyadenylation sequence, lox2272 site, pSP73 vector and lox511 site) inserted into intron 1. Western blot analysis confirmed the absence of protein expression in the brain. (J:110088, J:187828)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Usp46 Mutation:  79 strains or lines available
References
Original:  J:187828 Imai S, et al., Ubiquitin-specific peptidase 46 (Usp46) regulates mouse immobile behavior in the tail suspension test through the GABAergic system. PLoS One. 2012;7(6):e39084
All:  3 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory