About   Help   FAQ
Gt(ROSA)26Sortm1(CAG-flpe)Hmpr
Targeted Allele Detail
Summary
Symbol: Gt(ROSA)26Sortm1(CAG-flpe)Hmpr
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Haydn Prosser
MGI ID: MGI:5438836
Gene: Gt(ROSA)26Sor  Location: Chr6:113044389-113054205 bp, - strand  Genetic Position: Chr6, 52.73 cM
Alliance: Gt(ROSA)26Sortm1(CAG-flpe)Hmpr page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:187956
Parent Cell Line:  JM8.F6 (ES Cell)
Strain of Origin:  C57BL/6N
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutation:    Insertion
 
Gt(ROSA)26Sortm1(CAG-flpe)Hmpr expression driven by 1 gene
 
Mutation details: An enhanced flp (flpe) cassette containing a splice acceptor site and driven by the CAG promoter was ligated to a downstream PGK-neo cassette and inserted at the endogenous locus. (J:187956)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: CAG (chicken)
Summary of all recombinase alleles driven by CAG.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gt(ROSA)26Sor Mutation:  993 strains or lines available
Notes
This allele has the same molecular structure as the existing Gt(ROSA)26Sor, but it was generated in the JM8F6 ES cell line derived from C57BL6/N.
References
Original:  J:187956 Ramirez-Solis R, et al., Direct Data Submission. MGI Direct Data Submission. 2012;
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory