Ids<tm1Eto> Targeted Allele Detail MGI Mouse (MGI:5439833)

Ids^tm1Eto
Targeted Allele Detail

Summary

Symbol:	Ids^tm1Eto
Name:	iduronate 2-sulfatase; targeted mutation 1, Yoshikatsu Eto
MGI ID:	MGI:5439833
Gene:	Ids Location: ChrX:69386675-69408690 bp, - strand Genetic Position: ChrX, 36.01 cM
Alliance:	Ids^tm1Eto page

Mutation
origin

Germline Transmission:	Earliest citation of germline transmission: J:188058
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Mutation
description

Allele Type:		Targeted (Null/knockout)
Mutation:		Intragenic deletion
		Exons 2 through 5 were deleted, creating a knock-out allele. (J:188058)

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Disease models

Expression

In Structures Affected by this Mutation:

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available
Carrying any Ids Mutation:	11 strains or lines available

References

Original:	J:188058 Higuchi T, et al., Enzyme replacement therapy (ERT) procedure for mucopolysaccharidosis type II (MPS II) by intraventricular administration (IVA) in murine MPS II. Mol Genet Metab. 2012 Sep;107(1-2):122-8
All:	4 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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