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Tg(Adam12-cre,-EGFP)1Lpe
Transgene Detail
Summary
Symbol: Tg(Adam12-cre,-EGFP)1Lpe
Name: transgene insertion 1, Lucie Peduto
MGI ID: MGI:5442695
Synonyms: Adam12-cre-ires-egfpTG, M12-CIG
Transgene: Tg(Adam12-cre,-EGFP)1Lpe  Location: unknown  
Alliance: Tg(Adam12-cre,-EGFP)1Lpe page
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Adam12-cre,-EGFP)1Lpe expression driven by 1 gene
 
Mutation detailsA cre-ires-EGFP coding sequence, including a polyA sequence was inserted into exon 1 of the Adam12 gene in a 200 kb BAC by homologous recombination. The sequence replaced the endogenous ATG translation start codon. The modified BAC was used to generate transgenic founders. Line information is not available. (J:188912)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Adam12 (species not specified)
Summary of all recombinase alleles driven by Adam12.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:188912 Dulauroy S, et al., Lineage tracing and genetic ablation of ADAM12(+) perivascular cells identify a major source of profibrotic cells during acute tissue injury. Nat Med. 2012 Aug;18(8):1262-70
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory