About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:18687 Lardelli M, et al., The novel Notch homologue mouse Notch 3 lacks specific epidermal growth factor-repeats and is expressed in proliferating neuroepithelium. Mech Dev. 1994 May;46(2):123-36
Assay type: RNA in situ
MGI Accession ID: MGI:5444437
Gene symbol: Notch3
Gene name: notch 3
Probe: Notch3 probe3
Probe preparation: Antisense labelled with S35 DNA
Visualized with: Autoradiography
Results
Specimen 4C: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: hindbrain Strong 4C
TS19: midbrain Strong 4C
TS19: ear Present 4C Authors report lower level of expression in otocyst.

Specimen 4F: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: neural tube ventricular layer Strong 4F
TS19: future spinal cord Present Regionally restricted 4F Lower levels of expression in the perineurium.
TS19: dorsal root ganglion Present 4F

Specimen not shown: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: surface ectoderm Present Expresssion in skin.

Specimen 5C,D: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: telencephalon ventricular layer Strong 5D , 5C
TS23: telencephalon Present Regionally restricted 5D , 5C
TS23: telencephalon marginal layer Weak 5C , 5D Much lower expression in the subventricular, intermediate and marginal zones.

Specimen 5G,H: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: telencephalon ventricular layer Present Uniform 5G , 5H Uniform levels of expression in all ventricular zones, including the ganglionic eminence (striatum) and massa intermedia.
TS23: ganglionic eminence Present 5H , 5G Uniform levels of expression in all ventricular zones, including the ganglionic eminence (striatum) and massa intermedia.
TS23: choroid plexus Absent 5G , 5H

Specimen 5K,L: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: nasal septum Strong 5L , 5K
TS23: olfactory epithelium Strong 5L , 5K
TS23: nose Strong Regionally restricted 5L , 5K Authors report high expression in other regions of olfactory mesoderm.

Specimen 6C,D: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: olfactory epithelium Present 6C , 6D
TS27: nasal septum Present Regionally restricted 6D , 6C Expression in two cellular arrays of cells in mesoderm of nasal septum.

Specimen not shown: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: brain ventricular layer Weak

Specimen not shown: postnatal day 5 (more )
Structure Level Pattern Image Note
TS28: cerebellum external granule cell layer Absent
TS28: hippocampus granule cell layer Absent

Specimen not shown: postnatal adult (more )
Structure Level Pattern Image Note
TS28: choroid plexus Absent


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
09/17/2024
MGI 6.24
The Jackson Laboratory