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Tg(Sim1-cre)#Lowl
Transgene Detail
Summary
Symbol: Tg(Sim1-cre)#Lowl
Name: transgene insertion, Bradford B Lowell
MGI ID: MGI:5447031
Synonyms: Sim1-cre
Transgene: Tg(Sim1-cre)#Lowl  Location: unknown  
Alliance: Tg(Sim1-cre)#Lowl page
Transgene
origin
Strain of Origin:  FVB
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Sim1-cre)#Lowl expression driven by 1 gene
 
Mutation details: The cre ATG was inserted via recombineering techniques, into the Sim1 ATG site of a BAC containing 137.1 kb of genomic C57BL/6 Sim1 sequences up to and including exon 8. The inserted cre sequence deleted the first 31 bp of the Sim1 gene. Lines 1 and 2 were generated. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:115192)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Sim1 (species not specified)
Summary of all recombinase alleles driven by Sim1.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 1 RNA-Seq or microarray experiment(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:189194 Chen M, et al., Gsalpha deficiency in the paraventricular nucleus of the hypothalamus partially contributes to obesity associated with Gsalpha mutations. Endocrinology. 2012 Sep;153(9):4256-65
All:  31 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory