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Epcamtm1.1Hmd
Targeted Allele Detail
Summary
Symbol: Epcamtm1.1Hmd
Name: epithelial cell adhesion molecule; targeted mutation 1.1, Hiroshi Hamada
MGI ID: MGI:5449521
Gene: Epcam  Location: Chr17:87943407-87958555 bp, + strand  Genetic Position: Chr17, 57.87 cM
Alliance: Epcamtm1.1Hmd page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:190580
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
    Flp-mediated recombination removed the beta-geo cassette and left exons 2 and 3 floxed. (J:190580)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Epcam Mutation:  33 strains or lines available
References
Original:  J:190580 Lei Z, et al., EpCAM contributes to formation of functional tight junction in the intestinal epithelium by recruiting claudin proteins. Dev Biol. 2012 Nov 15;371(2):136-45
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory