Cyp2s1<tm1Ding> Targeted Allele Detail MGI Mouse (MGI:5449902)

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Cyp2s1^tm1Ding
Targeted Allele Detail

Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Summary

Symbol:	Cyp2s1^tm1Ding
Name:	cytochrome P450, family 2, subfamily s, polypeptide 1; targeted mutation 1, Xinxin Ding
MGI ID:	MGI:5449902
Gene:	Cyp2s1 Location: Chr7:25501894-25515950 bp, - strand Genetic Position: Chr7, 14.05 cM
Alliance:	Cyp2s1^tm1Ding page

Mutation
origin

Germline Transmission:	Earliest citation of germline transmission: J:190445
Parent Cell Line:	Bruce 4 (ES Cell)
Strain of Origin:	B6.Cg-Thy1^a

Mutation
description

Allele Type:		Targeted (Null/knockout)
Mutations:		Insertion, Intragenic deletion
		Mutation details: Exon 3 was replaced with a hygromycin resistance gene cassette and loxP site via homologous recombination. (J:190445)

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available Cell Lines: 0 lines available
Carrying any Cyp2s1 Mutation:	29 strains or lines available

References

Original:	J:190445 Wei Y, et al., Generation and Characterization of a Novel Cyp2a(4/5)bgs-Null Mouse Model. Drug Metab Dispos. 2013 Jan;41(1):132-40
All:	2 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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