Tg(Pbsn-cre/Esr1*)14Abch
Transgene Detail
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| Symbol: |
Tg(Pbsn-cre/Esr1*)14Abch |
| Name: |
transgene insertion 14, Andreas Birbach |
| MGI ID: |
MGI:5461708 |
| Synonyms: |
ProbasinBAC-MerCreMer |
| Transgene: |
Tg(Pbsn-cre/Esr1*)14Abch Location: unknown
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| Alliance: |
Tg(Pbsn-cre/Esr1*)14Abch page
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| Transgene Type: |
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Transgenic (Inducible, Recombinase) |
| Inducer: |
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tamoxifen |
| Mutation: |
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Insertion
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Tg(Pbsn-cre/Esr1*)14Abch expression driven by
1 gene
Transgene expression driven by:
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Mutation details: A BAC (#RP23-456A6; containing the entire mouse probasin (Pbsn) gene) was modified to insert a MerCreMer sequence (a double fusion of the cre recombinase cDNA sequence flanked on each end with a mutated murine estrogen receptor (mer) ligand-binding domain, resulting in tamoxifen-inducible cre expression) driven by the Pbsn promoter/enhancer region. The construct was microinjected into fertilized C57BL/6NCrl oocytes. Founder line 14 was established by breeding the founder, carrying 8-11 copies of the transgene, to wild-type C57BL/6J mice.
(J:154786)
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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Pbsn
(mouse)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 2 strains available
Cell Lines: 0 lines available
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| Original: |
J:154786 Birbach A, et al., A Probasin-MerCreMer BAC allows inducible recombination in the mouse prostate. Genesis. 2009 Nov;47(11):757-64 |
| All: |
2 reference(s) |
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Analysis Tools
