Tg(SFTPC-cre/ERT2)F42Kfx
Transgene Detail
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| Symbol: |
Tg(SFTPC-cre/ERT2)F42Kfx |
| Name: |
transgene insertion F42, Kai-Feng Xu |
| MGI ID: |
MGI:5465199 |
| Synonyms: |
SPC-Cre-ERT2 |
| Transgene: |
Tg(SFTPC-cre/ERT2)F42Kfx Location: unknown
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| Alliance: |
Tg(SFTPC-cre/ERT2)F42Kfx page
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| Transgene Type: |
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Transgenic (Inducible, Recombinase) |
| Inducer: |
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tamoxifen |
| Mutation: |
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Insertion
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Tg(SFTPC-cre/ERT2)F42Kfx expression driven by
1 gene
Transgene expression driven by:
| Organism |
Driver Gene |
Homolog in Mouse |
Note |
| human |
SFTPC (6440) |
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Mutation details: A 9.5 kb construct encoding SFTPC-cre/ERT2 (human surfactant associated protein C gene driving cre fused to a mutated estrogen receptor sequence; ERT2) was microinjected into mouse embryos to generated transgenic mice. Five founders were generated, but cre/ERT2 protein was stably expressed after tamoxifen injection by the progeny of only 2 lines, F42 and F67. These two lines were propagated for further experiments. Line F42 was entered as a representative line.
(J:192111)
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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SFTPC
(human)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:192111 Gui YS, et al., SPC-Cre-ERT2 transgenic mouse for temporal gene deletion in alveolar epithelial cells. PLoS One. 2012;7(9):e46076 |
| All: |
3 reference(s) |
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Analysis Tools
