About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:32724 Hierck BP, et al., Differential expression of alpha-6 and other subunits of laminin binding integrins during development of the murine heart. Dev Dyn. 1996 May;206(1):100-11
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5467139
Gene symbol: Itgb1
Gene name: integrin beta 1 (fibronectin receptor beta)
Antibody: anti-beta1
Detection system: Secondary antibody coupled to horseradish peroxidase
Results
Specimen 3b: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: endocardial cushion Strong Regionally restricted 3b , 3d Intense staining at the site where the developing valves faced each other.
TS21: endocardial tissue Strong Regionally restricted 3b Endocardium lining the outflow ridges and developing semilunar valves was highly positive.
TS21: aortic valve Present Graded 3b Expressed in a gradient in the mesenchyme of the atrioventricular valves from lateral (highly positive) to central (moderately positive).
TS21: mitral valve Present Graded 3b Expressed in a gradient in the mesenchyme of the atrioventricular valves from lateral (highly positive) to central (moderately positive).
TS21: pulmonary valve Present Graded 3b Expressed in a gradient in the mesenchyme of the atrioventricular valves from lateral (highly positive) to central (moderately positive).
TS21: tricuspid valve Present Graded 3b Expressed in a gradient in the mesenchyme of the atrioventricular valves from lateral (highly positive) to central (moderately positive).
TS21: atrium endocardial lining Moderate 3b
TS21: ventricle endocardial lining Moderate 3b
Specimen 3f: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: atrium endocardial lining Moderate 3f
TS21: ventricle endocardial lining Moderate 3f
TS21: arterial system Present Regionally restricted 3f Expressed in all endothelium.
TS21: venous system Present Regionally restricted 3f Expressed in all endothelium. Expression in the large veins was less positive than in the arteries.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
06/12/2024
MGI 6.13 		The Jackson Laboratory