Wnt16<tm1Lex> Targeted Allele Detail MGI Mouse (MGI:5467557)

Wnt16^tm1Lex
Targeted Allele Detail

Summary

Symbol:	Wnt16^tm1Lex
Name:	wingless-type MMTV integration site family, member 16; targeted mutation 1, Lexicon Genetics
MGI ID:	MGI:5467557
Synonyms:	Wnt16^-,exon1-3
Gene:	Wnt16 Location: Chr6:22288226-22298521 bp, + strand Genetic Position: Chr6, 9.22 cM, cytoband A3
Alliance:	Wnt16^tm1Lex page

Mutation
origin

Germline Transmission:	Earliest citation of germline transmission: J:188156
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129S5/SvEvBrd
Project Collection:	Lexicon

Mutation
description

Allele Type:		Targeted (Null/knockout, Reporter)
Mutations:		Insertion, Intragenic deletion
		A lacZ and floxed neo cassette replaced exons 1, 2 and 3. (J:188156, J:227247)

Generation of the Wnt16^tm1Lex allele

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Expression

In Structures Affected by this Mutation:

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available Cell Lines: 0 lines available
Carrying any Wnt16 Mutation:	31 strains or lines available

References

Original:	J:188156 Zheng HF, et al., WNT16 influences bone mineral density, cortical bone thickness, bone strength, and osteoporotic fracture risk. PLoS Genet. 2012 Jul;8(7):e1002745
All:	4 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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