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Gene Expression Data
Assay Details
Assay
Reference: J:58583 Fukada K, et al., In situ hybridisation study of type I, II, X collagens and aggrecan mRNas in the developing condylar cartilage of fetal mouse mandible. J Anat. 1999 Oct;195(Pt 3):321-9
Assay type: RNA in situ
MGI Accession ID: MGI:5468296
Gene symbol: Col1a2
Gene name: collagen, type I, alpha 2
Probe: p-alpha-2R2 cDNA
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 1a & 1c: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: mandible Present Regionally restricted 1a , 1c Expression was detected in cells adjacent to the posterior edge of the ossifying mandible. Expression was also noted posteriorly in the mesenchymal cell aggregation.

Specimen 2b: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: mandible Present Regionally restricted 2b Expression was high in periosteal osteogenic cells. High expression was detected in hypertrophic chondrocytes of the cartilage matrix.

Specimen 3b: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: mandible Present Regionally restricted 3b Expression was detected in the periosteal osteogenic cells surrounding the cartilaginous tissue. Slight expression was noted in the fibrous cell layer to the upper hypertrophic layer but is hardly detectable in the lower half of the hypertrophic layer.

Specimen 5b: embryonic day 18.0 (more )
Structure Level Pattern Image Note
TS26: mandible Weak Regionally restricted 5b The expression level in the condylar cartilage decreased, but it's localization was almost the same as at E16.0.

Specimen 6b: embryonic day 13.0 (more )
Structure Level Pattern Image Note
TS21: tibia-fibula pre-cartilage condensation Present Regionally restricted 6b Expression was detected in the chondrocytes and in the osteogenic cells surrounding the cartilaginous tissue.

Specimen 6g: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: tibia cartilage condensation Present Regionally restricted 6g Expression was detected in the chondrocytes at the epiphysis, gradually decreased toward the depths, and was not detected in the hypertrophic chondrocytes of the diaphysis.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
06/12/2024
MGI 6.13
The Jackson Laboratory