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Tg(Nphs1-cre)#Seq
Transgene Detail
Summary
Symbol: Tg(Nphs1-cre)#Seq
Name: transgene insertion, Susan E Quaggin
MGI ID: MGI:5468313
Synonyms: Nphs1-Cre, Pod-Cre, Podocin-Cre
Transgene: Tg(Nphs1-cre)#Seq  Location: unknown  
Alliance: Tg(Nphs1-cre)#Seq page
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Nphs1-cre)#Seq expression driven by 1 gene
 
Mutation detailsA mouse Neph1 promoter fused to a cre recombinase gene was used for the transgene. A 4.125 kb fragment of the mouse Neph1 promoter was used to drive transgene expression in podocytes. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:82024)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Nphs1 (mouse)
Summary of all recombinase alleles driven by Nphs1.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:193210 Jin J, et al., Soluble FLT1 binds lipid microdomains in podocytes to control cell morphology and glomerular barrier function. Cell. 2012 Oct 12;151(2):384-99
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory