TgTn(sb-Tyr)2172Ove
Transgene Detail
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| Symbol: |
TgTn(sb-Tyr)2172Ove |
| Name: |
transgenic transposon concatemer 2172, Paul A Overbeek |
| MGI ID: |
MGI:5473269 |
| Synonyms: |
OVB2172 |
| Transgene: |
TgTn(sb-Tyr)2172Ove Location: unknown
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| Alliance: |
TgTn(sb-Tyr)2172Ove page
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| Strain of Origin: |
Not Specified
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| Transgene Type: |
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Transgenic (Transposon concatemer) |
| Mutation: |
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Insertion
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Mutation details: A Sleeping Beauty (SB) transposon transgenic approach was used to generate these mice. The pT2-BART3 transposon vector used here has (from 5' to 3') an inverted repeat/direct repeat sequence (IR/DR; the SB transposon recognition site [280 bp]), an AD2 splice acceptor and polyA sequence, the tyrosinase minigene TyBS, a loxP site, a polyA sequence, a Hox9c splice acceptor, and right IR/DR (280 bp). The IR/DR sequences are outward-facing. The 4.1 kb tyrosinase minigene (TyBS) contains the tyrosinase upstream regulatory sequences (2.1 kbp from the BALB/c tyrosinase promoter and the first 65 bp of exon 1), followed by the C57BL/6-derived Tyrs-J cDNA sequence (1.9 kbp including cysteine at amino acid 103, glycine at amino acid 346, and the stop codon with polyA signal).
(J:192196)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:192196 Hicks AN, et al., Nicotinamide mononucleotide adenylyltransferase 2 (Nmnat2) regulates axon integrity in the mouse embryo. PLoS One. 2012;7(10):e47869 |
| All: |
1 reference(s) |
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Analysis Tools
