Summary | Transgene origin | Transgene description | Expression | Recombinase activity | Phenotypes | Tumor data | Find Mice (IMSR) | References

Symbol:	Tg(Vil1-cre)1000Gum
Name:	transgene insertion 1000, Deborah L Gumucio
MGI ID:	MGI:5474779
Synonyms:	VCre1000, Vil-Cre 1000, Villin-Cre 1000
Transgene:	Tg(Vil1-cre)1000Gum  Location: unknown
Alliance:	Tg(Vil1-cre)1000Gum page

Strain of Origin:

C57BL/6J x SJL/J

Transgene Type:    Transgenic (Recombinase) Mutation:    Insertion   Tg(Vil1-cre)1000Gum expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note mouse Vil1 (MGI:98930)   Mutation details: A transgenic construct containing the coding domain of Cre recombinase, driven by a 12.4 kb fragment of the mouse villin 1 gene, and a metallothionein polyadenylation site sequence was injected into the pronuclei of fertilized C57BL/6J x SJL/J mouse eggs. Seven lines were generated. Founder line 1000 was subsequently established. (J:78815)

Activity:	Tissue activity of this recombinase allele
Driver:	Vil1 (mouse) Summary of all recombinase alleles driven by Vil1. Comparative matrix view of recombinase activities Alliance mouse Vil1 gene page

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

3 assay results 5 RNA-Seq or microarray experiment(s)

List all tumor models in MMHCdb carrying Tg(Vil1-cre)1000Gum

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 2 strains available      Cell Lines: 0 lines available

Original:	J:78815 Madison BB, et al., cis Elements of the Villin Gene Control Expression in Restricted Domains of the Vertical (Crypt) and Horizontal (Duodenum, Cecum) Axes of the Intestine. J Biol Chem. 2002 Sep 6;277(36):33275-83
All:	97 reference(s)