Mlanatm1.1Bee
Targeted Allele Detail
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| Symbol: |
Mlanatm1.1Bee |
| Name: |
melan-A; targeted mutation 1.1, Friedrich Beermann |
| MGI ID: |
MGI:5476658 |
| Synonyms: |
MART-1fl, MlanaloxP |
| Gene: |
Mlana Location: Chr19:29675224-29686034 bp, + strand Genetic Position: Chr19, 24.28 cM, cytoband C2
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| Alliance: |
Mlanatm1.1Bee page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:194886
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| Parent Cell Line: |
Not Specified (ES Cell)
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| Strain of Origin: |
129S/SvEv
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| Allele Type: |
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Targeted (Conditional ready, No functional change) |
| Mutation: |
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Insertion
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Mutation details: This allele, which resulted from FLP recombinase-mediated deletion of a frt site-flanked neomycin resistance cassette, contains loxP sites flanking exon 2, containing the translation initiating ATG, and exon 3; the floxed exons encode the transmembrane domain of the protein. A single frt site remains in intron 1.
(J:194886)
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| Original: |
J:194886 Aydin IT, et al., Coat color dilution in mice because of inactivation of the melanoma antigen MART-1. Pigment Cell Melanoma Res. 2012 Jan;25(1):37-46 |
| All: |
1 reference(s) |
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Analysis Tools
