Tg(Myh6-icre/ERT2)#Wet
Transgene Detail
|
|
| Symbol: |
Tg(Myh6-icre/ERT2)#Wet |
| Name: |
transgene insertion, Nina Wettschureck |
| MGI ID: |
MGI:5477906 |
| Synonyms: |
alphaMHC-CreERT2 |
| Transgene: |
Tg(Myh6-icre/ERT2)#Wet Location: unknown
|
| Alliance: |
Tg(Myh6-icre/ERT2)#Wet page
|
|
|
|
| Transgene Type: |
|
Transgenic (Inducible, Recombinase) |
| Inducer: |
|
tamoxifen |
| Mutation: |
|
Insertion
|
| |
|
Tg(Myh6-icre/ERT2)#Wet expression driven by
1 gene
Transgene expression driven by:
| Organism |
Driver Gene |
Note |
| mouse |
Myh6 (MGI:97255) |
|
|
| |
|
Mutation details: The mouse promoter drives cardiac-specific expression of a tamoxifen-inducible humanized cre (icre) fused to an estrogen receptor mutant (ERT2) followed by a bovine growth hormone polyadenylation sequence. Flp-mediated recombination removed an FRT-flanked Lactb gene. The pound symbol (#) is used when no line is specified and/or lines are pooled.
(J:195335)
|
|
|
|
Activity: |
 Tissue activity of this recombinase allele
|
|
Driver:
|
Myh6
(mouse)
|
| |
|
|
View phenotypes and curated references for all genotypes (concatenated display).
|
| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
|
|
| Original: |
J:195335 Takefuji M, et al., G(13)-mediated signaling pathway is required for pressure overload-induced cardiac remodeling and heart failure. Circulation. 2012 Oct 16;126(16):1972-82 |
| All: |
18 reference(s) |
|
Analysis Tools
