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Tg(TNS4-cre)1Shlo
Transgene Detail
Summary
Symbol: Tg(TNS4-cre)1Shlo
Name: transgene insertion 1, Su Hao Lo
MGI ID: MGI:5484658
Synonyms: pCTEN-Cre
Transgene: Tg(TNS4-cre)1Shlo  Location: unknown  
Alliance: Tg(TNS4-cre)1Shlo page
Transgene
origin
Strain of Origin:  (C57BL/6 x CBA)F1
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(TNS4-cre)1Shlo expression driven by 1 gene
 
Mutation details: The final transgenic construct contained a 327-bp fragment from -290 to +37, of the human TNS4 (tensin 4; CTEN) promoter, a synthetic intron sequence, cre recombinase cDNA with a nuclear localization signal, and an SV40 polyadenylation signal. The construct was microinjected into (C57BL/6 x CBA)F1 zygotes. No founder information or line numbers are available. Crosses with reporter mice show strong cre activity in the brain and prostate, occasional staining in islets in the pancreas, bronchiole epithelium of the lung and in some tubules of the testis. No activity is observed in the kidney, small intestine, thymus, heart, tongue, liver, spleen or mammary gland. (J:195302)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: TNS4 (human)
Summary of all recombinase alleles driven by TNS4.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:195302 Chen NT, et al., Phylogenetic analysis, expression patterns, and transcriptional regulation of human CTEN gene. Gene. 2013 May 15;520(2):90-7
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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11/12/2024
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