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Fmo4tm1Eshe
Targeted Allele Detail
Summary
Symbol: Fmo4tm1Eshe
Name: flavin containing monooxygenase 4; targeted mutation 1, Elizabeth A Shephard
MGI ID: MGI:5487814
Gene: Fmo4  Location: Chr1:162620757-162641541 bp, - strand  Genetic Position: Chr1, 70.34 cM
Mutation
origin
Germline Transmission:  Unknown
Parent Cell Line:  E14TG2a (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted
Mutation:    Insertion
 
Mutation detailsA puro cassette, loxP site, 3' human HPRT minigene and a second copy of exon 7 were inserted downstream of the endogenous exon 7. (J:196270)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Fmo4 Mutation:  42 strains or lines available
Notes
This allele was generated in ES cells containing Fmo2tm1Eshe.
References
Original:  J:196270 Hernandez D, et al., Deletion of the mouse Fmo1 gene results in enhanced pharmacological behavioural responses to imipramine. Pharmacogenet Genomics. 2009 Apr;19(4):289-99
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory