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Gtf2itm1Lro
Targeted Allele Detail
Summary
Symbol: Gtf2itm1Lro
Name: general transcription factor II I; targeted mutation 1, L Osborne
MGI ID: MGI:5490967
Synonyms: Gtf2i3'UTRloxP
Gene: Gtf2i  Location: Chr5:134266688-134343614 bp, - strand  Genetic Position: Chr5, 74.48 cM
Alliance: Gtf2itm1Lro page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:196809
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Not Applicable)
Mutation:    Insertion
    A loxP site was inserted into the 3'UTR downstream of exon 34. (J:196809)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gtf2i Mutation:  139 strains or lines available
References
Original:  J:196809 Mervis CB, et al., Duplication of GTF2I results in separation anxiety in mice and humans. Am J Hum Genet. 2012 Jun 8;90(6):1064-70
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory