b2b2012Clo
Chemically induced Allele Detail
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| Symbol: |
b2b2012Clo |
| Name: |
Mutant line 2012; Bench to Bassinet Program (B2B/CVDC), mutation 2012 Cecilia Lo |
| MGI ID: |
MGI:5491231 |
| Synonyms: |
Cyclops |
| Gene: |
b2b2012Clo Location: unknown
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| Alliance: |
b2b2012Clo page
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Mutant has parallel outflow tracts indicating possible double outlet right ventricle (DORV), which was confirmed by ECM histopathology.
Show the 24 phenotype image(s) involving this allele.
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| Strain of Origin: |
C57BL/6J
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| Project Collection: |
B2B/CvDC
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| Allele Type: |
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Chemically induced (ENU) |
| Mutation: |
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Undefined
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Mutation details: This ENU-induced mutation was isolated in a screen at the University of Pittsburgh. More than one mutation in this line results in a discernible phenotype in a homozygous recessive screen. At least two segregating phenotype groups are identified. See b2b2012.1Clo and b2b2012.2Clo.
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any b2b2012Clo Mutation: |
0 strains or lines available
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Summative Diagnosis:
Mutant Type 1:
Cardiovascular phenotypes: Double outlet right ventricle (DORV) with ventricular septal defect (VSD), and atrioventricular septal defect (AVSD).
Noncardiovascular phenotype: Craniofacial defects including short snout, micropthalmia, anophthalmia and micrognathia.
Mutant Type 2:
Cardiovascular phenotypes: Biventricular hypertrophy, Right aortic arch (RAA)
Noncardiovascular phenotype: Craniofacial defects including micrognathia, anopthalmia, cyclopia, astomia, holoprosencephaly
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Analysis Tools
