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Gene Expression Data
Assay Details
Assay
Reference: J:110707 Pattyn A, et al., Delays in neuronal differentiation in Mash1/Ascl1 mutants. Dev Biol. 2006 Jul 1;295(1):67-75
Assay type: RNA in situ
MGI Accession ID: MGI:5495273
Gene symbol: Hand2
Gene name: heart and neural crest derivatives expressed 2
Probe: dHAND probe13
Probe preparation: labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 6A WT: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: sympathetic nervous system Present Regionally restricted 6A WT dHAND Expression in sympathoblasts aggregating around the dorsal aorta.
Specimen 6A Mash1-/-: embryonic day 10.5; Ascl1tm1And/Ascl1tm1And (more )
Structure Level Pattern Image Note
TS17: sympathetic nervous system Absent 6A Mash1-/- dHAND
Specimen 6B WT: embryonic day 11.5; Ascl1tm1And/Ascl1tm1And (more )
Structure Level Pattern Image Note
TS19: thoracic ganglion Present 6B WT dHAND
Specimen 6B Mash1-/-: embryonic day 11.5; Ascl1tm1And/Ascl1tm1And (more )
Structure Level Pattern Image Note
TS19: thoracic ganglion Weak 6B Mash1-/- dHAND Reduced number of expressing cells compared with wild type embryos.
Specimen 6C WT: embryonic day 12.5; Ascl1tm1And/Ascl1tm1And (more )
Structure Level Pattern Image Note
TS20: thoracic ganglion Present 6C WT dHAND
Specimen 6C Mash1-/-: embryonic day 12.5; Ascl1tm1And/Ascl1tm1And (more )
Structure Level Pattern Image Note
TS20: thoracic ganglion Present 6C Mash1-/- dHAND
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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06/12/2024
MGI 6.13 		The Jackson Laboratory