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Tg(Tff2-cre/ERT2)#Tcw
Transgene Detail
Summary
Symbol: Tg(Tff2-cre/ERT2)#Tcw
Name: transgene insertion, Timothy C Wang
MGI ID: MGI:5496138
Synonyms: TFF2-BAC-CreERT2, Tff2-CreERT2, TFF2-CreERT2, TFF2 CreERTM
Transgene: Tg(Tff2-cre/ERT2)#Tcw  Location: unknown  
Alliance: Tg(Tff2-cre/ERT2)#Tcw page
Transgene
origin
Strain of Origin:  (CBA x C57BL/6J)F1
Transgene
description
Transgene Type:    Transgenic (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Tg(Tff2-cre/ERT2)#Tcw expression driven by 1 gene
 
Mutation detailsUsing recombineering methods, a cre/ERT2 cassette was inserted at the ATG codon in exon 1 of the Tff2 gene in the BAC RP24-335C10. The modified BAC construct was injected into fertilized CBA x C57BL/6J oocytes. Three founders positive for the transgene were obtained and F4 or F5 generations were crossed to reporter mice for analyses. The three lines show similar recombination patterns and 2 of these were used to carry out further experiments. (J:198266)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Tff2 (mouse)
Summary of all recombinase alleles driven by Tff2.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:198266 Quante M, et al., TFF2 mRNA transcript expression marks a gland progenitor cell of the gastric oxyntic mucosa. Gastroenterology. 2010 Dec;139(6):2018-2027.e2
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/17/2024
MGI 6.24
The Jackson Laboratory