Tg(Tff2-cre/ERT2)#Tcw
Transgene Detail
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Symbol: |
Tg(Tff2-cre/ERT2)#Tcw |
Name: |
transgene insertion, Timothy C Wang |
MGI ID: |
MGI:5496138 |
Synonyms: |
TFF2-BAC-CreERT2, Tff2-CreERT2, TFF2-CreERT2, TFF2 CreERTM |
Transgene: |
Tg(Tff2-cre/ERT2)#Tcw Location: unknown
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Alliance: |
Tg(Tff2-cre/ERT2)#Tcw page
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Transgene Type: |
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Transgenic (Inducible, Recombinase) |
Inducer: |
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tamoxifen |
Mutation: |
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Insertion
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Tg(Tff2-cre/ERT2)#Tcw expression driven by
1 gene
Transgene expression driven by:
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Mutation details: Using recombineering methods, a cre/ERT2 cassette was inserted at the ATG codon in exon 1 of the Tff2 gene in the BAC RP24-335C10. The modified BAC construct was injected into fertilized CBA x C57BL/6J oocytes. Three founders positive for the transgene were obtained and F4 or F5 generations were crossed to reporter mice for analyses. The three lines show similar recombination patterns and 2 of these were used to carry out further experiments.
(J:198266)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Tff2
(mouse)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Original: |
J:198266 Quante M, et al., TFF2 mRNA transcript expression marks a gland progenitor cell of the gastric oxyntic mucosa. Gastroenterology. 2010 Dec;139(6):2018-2027.e2 |
All: |
2 reference(s) |
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