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Tg(Ucp1-cre/ERT2)426Biat
Transgene Detail
Summary
Symbol: Tg(Ucp1-cre/ERT2)426Biat
Name: transgene insertion 426, Biomodels Austria
MGI ID: MGI:5498561
Synonyms: Ucp1-CreER
Transgene: Tg(Ucp1-cre/ERT2)426Biat  Location: unknown  
Alliance: Tg(Ucp1-cre/ERT2)426Biat page
Transgene
origin
Strain of Origin:  C57BL/6N
Transgene
description
Transgene Type:    Transgenic (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Tg(Ucp1-cre/ERT2)426Biat expression driven by 1 gene
 
Mutation detailsSequences encoding a cre/ERT2 fusion protein, Frt-flanked neo cassette, and a polyadenylation signal were inserted into a BAC containing the Ucp1 promoter by recombineering methods. The neo marker was not removed, as the original construct showed more efficient cre activity. The purified construct was microinjected into fertilized C57BL/6N oocytes. Line 426 was established. (J:198491)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Ucp1 (species not specified)
Summary of all recombinase alleles driven by Ucp1.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:198491 Rosenwald M, et al., Bi-directional interconversion of brite and white adipocytes. Nat Cell Biol. 2013 Jun;15(6):659-67
All:  28 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory