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Gene Expression Data
Assay Details
Assay
Reference: J:76824 Kim M, et al., Region-specific expression of the helix-loop-helix gene BETA3 in developing and adult brains. Mech Dev. 2002 Jun;114(1-2):125
Assay type: RNA in situ
MGI Accession ID: MGI:5499096
Gene symbol: Bhlhe22
Gene name: basic helix-loop-helix family, member e22
Probe: BETA3 probe
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 2A: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: telencephalon Present Regionally restricted 2A Expression is in the preplate.
TS19: telencephalon ventricular layer Absent 2A

Specimen 2B: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: cortical plate Very strong 2B
TS21: cerebral cortex ventricular layer Absent 2B
TS21: ganglionic eminence Absent 2B

Specimen 2C,D: embryonic day 13.5 (more )
Note: (D) Higher magnification of the boxed area in (C).
Structure Level Pattern Image Note
TS21: cortical plate Very strong 2C , 2D
TS21: thalamus Present Regionally restricted 2C Expression is in the thalamic eminences in the ventral thalamus.
TS21: cerebral cortex ventricular layer Absent 2D , 2C
TS21: ganglionic eminence Absent 2D , 2C

Specimen 2E,F: embryonic day 13.5 (more )
Note: (F) Higher magnification of the boxed area in (E).
Structure Level Pattern Image Note
TS21: thalamus Present Regionally restricted 2F , 2E Expression is in a ribbon of cells lateral to the ventricular zone of the third ventricle.

Specimen 2G: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: cortical plate Strong 2G
TS23: cerebral cortex intermediate zone Present 2G
TS23: cerebral cortex subventricular zone Present 2G

Specimen 2H: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: hippocampus Present 2H
TS23: ganglionic eminence Absent 2H
TS23: midbrain Absent 2H

Specimen 2I: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: cerebral cortex subventricular zone Present 2I Expression breaks abruptly at the junction of the neo- and piriform cortices.
TS25: cortical plate Present 2I Expression breaks abruptly at the junction of the neo- and piriform cortices.
TS25: hippocampus Present 2I Expression breaks abruptly at the junction of the neo- and piriform cortices.

Specimen 3A: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: cingulate cortex Strong Regionally restricted 3A Expression is in the superficial layers.
TS27: neocortex layer Strong Regionally restricted 3A Expression is in the superficial layers.

Specimen 3B: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: cingulate cortex Strong Regionally restricted 3B Expression is in the superficial layers.
TS27: neocortex layer Strong Regionally restricted 3B Expression is in the superficial layers.
TS27: dentate gyrus Very strong 3B
TS27: hippocampus CA1 Very strong 3B
TS27: hippocampus CA2 Very strong 3B
TS27: hippocampus CA3 Very strong 3B
TS27: hippocampus CA4 Very strong 3B

Specimen 3C: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: piriform cortex Weak Regionally restricted 3C Expression is in the upper layer.

Specimen 3D,E: postnatal day 1 (more )
Note: (E) Higher magnification of the boxed area in (D).
Structure Level Pattern Image Note
TS27: cerebellum Purkinje cell layer Present 3E , 3D
TS27: cerebellum internal granule cell layer Present 3E , 3D

Specimen 3F: postnatal day 3 (more )
Structure Level Pattern Image Note
TS27: hippocampus Very strong 3F
TS27: neocortex layer Present Regionally restricted 3F Expression is in the upper layers.

Specimen 3G: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: hippocampus Very strong 3G
TS28: neocortex layer Weak Regionally restricted 3G Expression is in the upper layers.

Specimen 3H: postnatal adult (more )
Structure Level Pattern Image Note
TS28: dentate gyrus Present 3H
TS28: hippocampus CA3 Present 3H
TS28: hippocampus CA1 Absent 3H
TS28: neocortex layer Absent 3H

Specimen not shown E15.5: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: spinal cord Absent


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
06/12/2024
MGI 6.13
The Jackson Laboratory