Arhgef26tm1.1Kbur
Targeted Allele Detail
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| Symbol: |
Arhgef26tm1.1Kbur |
| Name: |
Rho guanine nucleotide exchange factor 26; targeted mutation 1.1, Keith Burridge |
| MGI ID: |
MGI:5500046 |
| Gene: |
Arhgef26 Location: Chr3:62245765-62369642 bp, + strand Genetic Position: Chr3, 29.97 cM
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| Alliance: |
Arhgef26tm1.1Kbur page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:195919
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| Parent Cell Line: |
Not Specified (ES Cell)
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| Strain of Origin: |
Not Specified
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| Allele Type: |
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Targeted (Null/knockout) |
| Mutations: |
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Insertion, Intragenic deletion
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Mutation details: A loxP site was inserted upstream of exon 4. An FRT-flanked neomycin resistance (neo) cassette with a 3' loxP site was inserted downstream of exon 5. Cre-mediated recombination removed exon 4, exon 5 and the neo cassette. Western blot analysis confirmed the absence of protein expression in the liver, lung and brain.
(J:195919)
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Generation of the Arhgef26tm1.1Kbur allele |
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Arhgef26 Mutation: |
51 strains or lines available
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| Original: |
J:195919 Samson T, et al., The guanine-nucleotide exchange factor SGEF plays a crucial role in the formation of atherosclerosis. PLoS One. 2013;8(1):e55202 |
| All: |
1 reference(s) |
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Analysis Tools
