Fbxw4tm1.2Fsp
Targeted Allele Detail
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| Symbol: |
Fbxw4tm1.2Fsp |
| Name: |
F-box and WD-40 domain protein 4; targeted mutation 1.2, Francois Spitz |
| MGI ID: |
MGI:5501266 |
| Synonyms: |
F4lox |
| Gene: |
Fbxw4 Location: Chr19:45566693-45648751 bp, - strand Genetic Position: Chr19, 38.75 cM
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| Alliance: |
Fbxw4tm1.2Fsp page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:196292
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| Parent Cell Line: |
E14 (ES Cell)
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| Strain of Origin: |
129P2/OlaHsd
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| Allele Type: |
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Targeted (Reporter) |
| Mutation: |
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Insertion
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Mutation details: A Sleeping Beauty cargo transgene was targeted downtream of exon 2 by homologous recombination. It contained a loxP site, lacZ gene, lox2272 site, insulator from HSS4 site of chicken beta-globin locus, loxP site, FRT-flanked neomycin (neo) resistance cassette and lox2272 site. Flp-mediated recombination removed the neo cassette. Cre-mediated recombination removed the lacZ and insulator and left a loxP site downstream of exon 2.
(J:196292)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Fbxw4 Mutation: |
28 strains or lines available
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| Original: |
J:196292 Marinic M, et al., An integrated holo-enhancer unit defines tissue and gene specificity of the Fgf8 regulatory landscape. Dev Cell. 2013 Mar 11;24(5):530-42 |
| All: |
1 reference(s) |
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Analysis Tools
