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Krt19tm1(cre/ERT2)Szki
Targeted Allele Detail
Summary
Symbol: Krt19tm1(cre/ERT2)Szki
Name: keratin 19; targeted mutation 1, Atsushi Suzuki
MGI ID: MGI:5506739
Synonyms: CK19-CreERT2
Gene: Krt19  Location: Chr11:100031636-100036752 bp, - strand  Genetic Position: Chr11, 63.42 cM
Alliance: Krt19tm1(cre/ERT2)Szki page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:192740
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Inducible, Recombinase)
Inducer:    tamoxifen
Mutations:    Insertion, Intragenic deletion
 
Krt19tm1(cre/ERT2)Szki expression driven by 1 gene
 
Mutation details: A cre/ERT2 cassette was inserted into exon 1 of the Krt19 gene by homologous recombination in ES cells. (J:192740)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Krt19 (mouse)
Summary of all recombinase alleles driven by Krt19.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Krt19 Mutation:  21 strains or lines available
References
Original:  J:192740 Sekiya S, et al., Intrahepatic cholangiocarcinoma can arise from Notch-mediated conversion of hepatocytes. J Clin Invest. 2012 Nov 1;122(11):3914-8
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory