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Tbx18tm1(cre/Esr1*)Ccai
Targeted Allele Detail
Summary
Symbol: Tbx18tm1(cre/Esr1*)Ccai
Name: T-box18; targeted mutation 1, Chen-Leng Cai
MGI ID: MGI:5507040
Synonyms: Tbx18MCM, Tbx18MerCreMer
Gene: Tbx18  Location: Chr9:87584853-87613313 bp, - strand  Genetic Position: Chr9, 47.06 cM, cytoband E3.2
Alliance: Tbx18tm1(cre/Esr1*)Ccai page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:196480
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Tbx18tm1(cre/Esr1*)Ccai expression driven by 1 gene
 
Mutation details: A cassette encoding cre recombinase fused to 2 mutated murine estrogen receptor ligand-binding domains (Mer; Esr1*) was inserted upstream of the endogenous ATG codon of Tbx18 by homologous recombination in ES cells. (J:137459, J:196480)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Tbx18 (mouse)
Summary of all recombinase alleles driven by Tbx18.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tbx18 Mutation:  36 strains or lines available
References
Original:  J:196480 Grisanti L, et al., Tbx18 targets dermal condensates for labeling, isolation, and gene ablation during embryonic hair follicle formation. J Invest Dermatol. 2013 Feb;133(2):344-53
All:  4 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
08/02/2024
MGI 6.24 		The Jackson Laboratory