Col1a1<tm13(neo/hygro*)Jae> Targeted Allele Detail MGI Mouse (MGI:5507043)

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Col1a1^{tm13(neo/hygro*)Jae}
Targeted Allele Detail

Summary | Mutation origin | Mutation description | Find Mice (IMSR) | Notes | References

Summary

Symbol:	Col1a1^{tm13(neo/hygro*)Jae}
Name:	collagen, type I, alpha 1; targeted mutation 13, Rudolf Jaenisch
MGI ID:	MGI:5507043
Gene:	Col1a1 Location: Chr11:94827050-94843868 bp, + strand Genetic Position: Chr11, 59.01 cM, cytoband D

Mutation
origin

Germline Transmission:	Unknown
Parent Cell Line:	KH2 (ES Cell)
Strain of Origin:	(C57BL/6 x 129S4/SvJae)F1

Mutation
description

Allele Type:		Targeted (RMCE-ready)
Mutation:		Insertion
		Mutation details: ES cells containing the Gt(ROSA)26Sor^{tm1(rtTAM2)Jae} allele were subsequently targeted to insert an FRT flanked PGK-neomycin resistance gene followed by a promoterless and ATG-less hygromycin resistance gene downstream of the Col1a1 gene. This allele can be used for RMCE. (J:98920*)

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available
Carrying any Col1a1 Mutation:	163 strains or lines available

Notes

This allele was used to generate: Col1a1^{tm1(tetO/CMV-Lep)Rll}, Col1a1^{tm1(tetO-CTNNB1)Tcd}, Col1a1^{tm1(tetO-Cyp26b1)Mfra}, Col1a1^{tm10(tetO-Dnmt3b_i3)Jae}, Col1a1^{tm10(tetO*-RFP/RNAi:Rpa3)Slowe}, Col1a1^{tm11(tetO-Dnmt3b_i6)Jae}, Col1a1^{tm11(tetO*-RFP/RNAi:Rpa3)Slowe}, Col1a1^{tm12(tetO-Dnmt3a_i1)Jae}, Col1a1^{tm13(tetO-GFP/RNAi:Brd4)Slowe}, Col1a1^{tm14(tetO-GFP/RNAi:Brd4)Slowe}, Col1a1^{tm15(tetO-GFP/RNAi:Ren)Slowe}, Col1a1^{tm16(tetO-GFP/RNAi:Trim33)Slowe}, Col1a1^{tm17(tetO-GFP,-cas9*)Slowe}, Col1a1^{tm18(tetO-GFP,-cas9*)Slowe}, Col1a1^{tm19(tetO-GFP,-cas9*)Slowe}, Col1a1^{tm1(CAG-Ezh2*)Meln}, Col1a1^{tm1(CMV/tetO-Kdm2b)Atz}, Col1a1^tm1(Sry)Aqui, Col1a1^{tm1(tetO-ACMSD)Mmf}, Col1a1^{tm1(tetO-cas9)Sho}, Col1a1^{tm1(tetO-Ccnb1)Jvd}, Col1a1^{tm1(tetO-CDKN2A)Ibp}, Col1a1^{tm1(tetO-Cdx1)Ywng}, Col1a1^{tm1(tetO-Deptor)Dmsa}, Col1a1^{tm1(tetO-Fos)Wag}, Col1a1^{tm1(tetO-Gata4/mCherry)Amza}, Col1a1^{tm1(tetO-GFP/RNAi:luc)Slowe}, Col1a1^{tm1(tetO-GFP/RNAi:Pax5)Radi}, Col1a1^{tm1(tetO-GFP/RNAi:rluc)Beggs}, Col1a1^{tm1(tetO-GFP/RNAi:Sirt1)Pyc}, Col1a1^{tm1(tetO-GFP/RNAi:Stat3)Ern}, Col1a1^{tm1(tetO-KMT2A/ELL)Dbry}, Col1a1^{tm1(tetO-Lin28a)Gqda}, Col1a1^{tm1(tetO-mCherry)Eggn}, Col1a1^{tm1(tetO-Msi1)Cjl}, Col1a1^{tm1(tetO-Pou5f1,-Klf4,-Sox2,-Myc)Hoch}, Col1a1^{tm1(tetO-RNAi:Ptgs2,GFP)Hahe}, Col1a1^{tm1(tetO-RNAi:Rps19)Karl}, Col1a1^{tm1(tetO-SOX2)Mjm}, Col1a1^{tm1(tetO-Stat1)Biat}, Col1a1^{tm1(tetO-Tcfap2c)Hsc}, Col1a1^{tm1(tetO-U2AF1*S34F)Mjwa}, Col1a1^{tm1(tetO-URI1)Ndj}, Col1a1^{tm1(tetO-YAP1*)Fcam}, Col1a1^{tm1(tetO-Yap1*)Lrsn}, Col1a1^{tm1(tetO-Yod1*)Hpl}, Col1a1^{tm20(tetO-GFP,-cas9*D10A)Slowe}, Col1a1^{tm2(CMV/tetO-Kdm2b*)Atz}, Col1a1^tm2(Sry)Aqui, Col1a1^{tm2(tetO-Ccnb2)Jvd}, Col1a1^{tm2(tetO-Fosl2,-DsRed)Wag}, Col1a1^{tm2(tetO-GFP/RNAi:Ren)Radi}, Col1a1^{tm2(tetO-GFP/RNAi:Rpl5)Beggs}, Col1a1^{tm2(tetO-GFP/RNAi:Trp53)Slowe}, Col1a1^{tm2(tetO-LIN28B)Gqda}, Col1a1^{tm2(tetO-RNAi:Rps19)Karl}, Col1a1^{tm2(tetO-U2AF1)Mjwa}, Col1a1^{tm2(tetO-URI1*S371A)Ndj}, Col1a1^{tm2(tetO-Yap1)Lrsn}, Col1a1^tm3(Sry)Aqui, Col1a1^{tm3(tet0-Ccne1)Jvd}, Col1a1^{tm3(tetO-Fosl1,-DsRed)Wag}, Col1a1^{tm3(tetO-GFP/RNAi:Apc)Slowe}, Col1a1^{tm3(tetO-Mirlet7g/Mir21)Gqda}, Col1a1^{tm3(tetO-Pou5f1,-Sox2,-Klf4,-Myc)Jae}, Col1a1^tm4(Sry)Aqui, Col1a1^{tm4(tetO-GFP/RNAi:Apc)Slowe}, Col1a1^{tm4(tetO-Jun/Fosl2)Wag}, Col1a1^{tm4(tetO-Pou5f1,-Sox2,-Klf4,-Myc)Jae}, Col1a1^tm5(Sry)Aqui, Col1a1^{tm5(tetO-GFP/RNAi:Cdkn2a)Slowe}, Col1a1^{tm5(tetO-Jun/Fos)Wag}, Col1a1^{tm5(tetO-Pou5f1,-Klf4,-Myc)Jae}, Col1a1^{tm6(tetO-GFP/RNAi:Cdkn2a)Slowe}, Col1a1^{tm6(tetO-Junb/Fos,-DsRed)Wag}, Col1a1^{tm6(tetO-MSI2)Jae}, Col1a1^{tm7(tetO-GFP/RNAi:rluc)Slowe}, Col1a1^{tm7(tetO-HIST1H2BJ/GFP)Jae}, Col1a1^{tm7(tetO-Jund/Fos)Wag}, Col1a1^{tm7(tetO-Pou5f1,-Klf4,-Sox2,-mCherry)Hoch}, Col1a1^{tm8(tetO-GFP/RNAi:Rpa3)Slowe}, Col1a1^{tm9(tetO-Dnmt3b_i1)Jae}, Col1a1^{tm9(tetO-GFP/RNAi:Rpa3)Slowe}, Col1a1^{tm1(Rr496-lacZ)Andg}, Col1a1^{tm2(Rr492-lacZ)Andg}, Col1a1^{tm3(Rr493-lacZ)Andg}, Col1a1^{tm4(Rr494-lacZ)Andg}, Col1a1^{tm5(Rr284304-lacZ)Andg}, Col1a1^{tm6(Rr284323-lacZ)Andg}.

References

Original:	J:98920 Hochedlinger K, et al., Ectopic expression of Oct-4 blocks progenitor-cell differentiation and causes dysplasia in epithelial tissues. Cell. 2005 May 6;121(3):465-77
All:	5 reference(s)

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