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Tg(Phox2b-flpo)3276Grds
Transgene Detail
Summary
Symbol: Tg(Phox2b-flpo)3276Grds
Name: transgene insertion 3276, Christo Goridis
MGI ID: MGI:5508639
Synonyms: Phox2b::FLPo
Transgene: Tg(Phox2b-flpo)3276Grds  Location: unknown  
Alliance: Tg(Phox2b-flpo)3276Grds page
Transgene
origin
Strain of Origin:  (C57BL/6 x DBA/2)F1
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Phox2b-flpo)3276Grds expression driven by 1 gene
 
Mutation details: A mouse bacterial artificial chromosome (BAC; RP24-95M11), containing the entire Phox2b (paired-like homeobox 2b) locus was obtained. This BAC also contained ~150kb sequence upstream of the Phox2b locus and ~50kb of sequence downstream of the Phox2b locus. A codon-optimized FLPo recombinase sequence fused with an SV40 polyadenylation signal, and a kanamycin resistance cassette were inserted into exon 2 of Phox2b. The resulting Phox2b::FLPo BAC transgene was injected into (C57BL/6 x DBA/2)F1 fertilized oocytes. (J:199321)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Phox2b (mouse)
Summary of all recombinase alleles driven by Phox2b.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:199321 Hirsch MR, et al., A Phox2b::FLPo transgenic mouse line suitable for intersectional genetics. Genesis. 2013 Jul;51(7):506-14
All:  13 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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11/12/2024
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