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Mboat7tm1Arai
Targeted Allele Detail
Summary
Symbol: Mboat7tm1Arai
Name: membrane bound O-acyltransferase domain containing 7; targeted mutation 1, Hiroyoki Arai
MGI ID: MGI:5509338
Synonyms: Lpiat1-
Gene: Mboat7  Location: Chr7:3680788-3696188 bp, - strand  Genetic Position: Chr7, 2.12 cM, cytoband A1
Alliance: Mboat7tm1Arai page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:200247
Parent Cell Line:  E14K (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation details: A neomycin resistance cassette replaced exons 2 through 4. Western blot analysis confirmed the absence of protein expression in the brain, liver, kidney, testis and lung. (J:200247)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 17 assay results
In Structures Affected by this Mutation: 4 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mboat7 Mutation:  19 strains or lines available
References
Original:  J:200247 Lee HC, et al., LPIAT1 regulates arachidonic acid content in phosphatidylinositol and is required for cortical lamination in mice. Mol Biol Cell. 2012 Dec;23(24):4689-700
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory