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Ctdnep1tm1Ryn
Targeted Allele Detail
Summary
Symbol: Ctdnep1tm1Ryn
Name: CTD nuclear envelope phosphatase 1; targeted mutation 1, Ryuichi Nishinakamura
MGI ID: MGI:5510826
Synonyms: Dullard-
Gene: Ctdnep1  Location: Chr11:69871994-69881427 bp, + strand  Genetic Position: Chr11, 42.95 cM, cytoband B4
Alliance: Ctdnep1tm1Ryn page
Arrested development and abnormal morphogenesis of extraembryonic tissues in Ctdnep1tm1Ryn/Ctdnep1tm1Ryn embryos

Show the 3 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:199855
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation details: A neomycin resistance cassette replaced the entire coding sequence. Q-PCR confirmed the absence of transcript expression in E7.5 embryos. (J:199855)
Generation of the Ctdnep1tm1Ryn allele
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation: 4 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ctdnep1 Mutation:  20 strains or lines available
References
Original:  J:199855 Tanaka SS, et al., Dullard/Ctdnep1 modulates WNT signalling activity for the formation of primordial germ cells in the mouse embryo. PLoS One. 2013;8(3):e57428
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory