Mterf1atm1.1Lrsn
Targeted Allele Detail
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| Symbol: |
Mterf1atm1.1Lrsn |
| Name: |
mitochondrial transcription termination factor 1a; targeted mutation 1.1, Nils-Goran Larsson |
| MGI ID: |
MGI:5514266 |
| Gene: |
Mterf1a Location: Chr5:3940581-3943933 bp, - strand Genetic Position: Chr5, 2.26 cM
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| Alliance: |
Mterf1atm1.1Lrsn page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:198969
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| Parent Cell Line: |
Not Specified (ES Cell)
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| Strain of Origin: |
Not Specified
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| Allele Type: |
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Targeted (Null/knockout) |
| Mutations: |
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Insertion, Intragenic deletion
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Mutation details: The second exon of Mterf1a was flanked by a loxP site and an FRT-flanked neomycin resistance cassette with a loxP site. This allele was generated in ES cells containing Mterf1btm1Lrsn on the same chromosome. Flp-mediated recombination removed the neomycin resistance cassette.
(J:198969)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Mterf1a Mutation: |
21 strains or lines available
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| Original: |
J:198969 Terzioglu M, et al., MTERF1 binds mtDNA to prevent transcriptional interference at the light-strand promoter but is dispensable for rRNA gene transcription regulation. Cell Metab. 2013 Apr 2;17(4):618-26 |
| All: |
1 reference(s) |
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Analysis Tools
