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Actbtm4(cre/ERT2)Npa
Targeted Allele Detail
Summary
Symbol: Actbtm4(cre/ERT2)Npa
Name: actin, beta; targeted mutation 4, Novartis Pharma AG
MGI ID: MGI:5514361
Gene: Actb  Location: Chr5:142888870-142892509 bp, - strand  Genetic Position: Chr5, 81.8 cM
Alliance: Actbtm4(cre/ERT2)Npa page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:199525
Parent Cell Line:  BALB/c-I (ES Cell)
Strain of Origin:  BALB/cJ
Mutation
description
Allele Type:    Targeted (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Actbtm4(cre/ERT2)Npa expression driven by 1 gene
 
Mutation details: Cre recombinase fused to the modified estrogen receptor sequence (ERT2) was inserted into the Actin beta gene by homologous recombination. (J:129105, J:199525)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Actb (mouse)
Summary of all recombinase alleles driven by Actb.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Actb Mutation:  53 strains or lines available
References
Original:  J:199525 Billich A, et al., Partial deficiency of sphingosine-1-phosphate lyase confers protection in experimental autoimmune encephalomyelitis. PLoS One. 2013;8(3):e59630
All:  4 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory