Pip<tm1Myal> Targeted Allele Detail MGI Mouse (MGI:5516489)

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Pip^tm1Myal
Targeted Allele Detail

Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Summary

Symbol:	Pip^tm1Myal
Name:	prolactin induced protein; targeted mutation 1, Yvonne Myal
MGI ID:	MGI:5516489
Synonyms:	mSMGP
Gene:	Pip Location: Chr6:41824483-41828999 bp, + strand Genetic Position: Chr6, 20.05 cM, cytoband B2
Alliance:	Pip^tm1Myal page

Mutation
origin

Germline Transmission:	Earliest citation of germline transmission: J:202016
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129S/SvEv

Mutation
description

Allele Type:		Targeted (Null/knockout)
Mutations:		Insertion, Intragenic deletion
		Mutation details: A neomycin resistance cassette replaced exon 2. Western blot analysis confirmed the absence of protein expression in the saliva and tears. (J:202016)

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Expression

In Structures Affected by this Mutation:

7 anatomical structure(s)

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available
Carrying any Pip Mutation:	16 strains or lines available

References

Original:	J:202016 Blanchard A, et al., Generation and initial characterization of the prolactin-inducible protein (PIP) null mouse: accompanying global changes in gene expression in the submandibular gland. Can J Physiol Pharmacol. 2009 Oct;87(10):859-72
All:	3 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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